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Search Results for " cd-1 mice "

9

Compounds

Cat No. Product Name Synonyms Targets
T36692 Fanotaprim DHFR
Fanotaprim is a dihydrofolate reductase (DHFR) inhibitor. Fanotaprim inhibits the growth of T. gondii strains with a TgDHFR IC50 of 1.57 ± 0.11 nM and a hDHFR IC50 of 308 ± 71 nM and a hDHFR to TgDHFR selectivity ratio o...
T40187 GNF2133 DYRK
GNF2133 is an effective and selective inhibitor of DYRK1A with IC50s of 6.2 nM. GNF2133 can be used in studies about type 1 diabetes.
T26619 Amitivir LY217896,LY 217896,LY-217896 Others , Influenza Virus
Amitivir (LY 217896) is an inosine monophosphate dehydrogenase inhibitor. Amitivir inhibits the replication of dividing MDCK cells. Amitivir was associated with asymptomatic rises in serum uric acid levels and was ineffe...
TP1882L1 Orphanin FQ(1-11) acetate(178249-41-7 free base) Opioid Receptor
Peptide fragment containing amino acids 1-11 of Nociceptin. Potent agonist of the ORL1/KOR-3 receptor (Ki = 55 nM); displays no affinity for opioid receptors, including μ, δ, κ1 and κ3 receptors (Ki >1000 nM). Displays a...
T6S0119 Dauricine Apoptosis , Others , NF-κB
1. Dauricine has pulmonary toxicity, can produce pulmonary injury in CD-1 mice by the metabolism of Dauricine mediated by CYP3A. 2. Dauricinec can pass the blood-brain barrier, and that P-glycoprotein has an important ro...
T83582 (±)-Pantothenic acid (±)-Vitamin B5,(±)-Pantothenate
(±)-Pantothenic acid ((±)-Pantothenate), a B-vitamin, is essential for coenzyme A (CoA) biosynthesis in mammalian cells and exhibits protective activity against valproic acid (VPA)-induced neural tube defects (NTD) in CD...
TP1882 Orphanin FQ(1-11) Orphanin FQ (1-11)
Peptide fragment containing amino acids 1-11 of Nociceptin. Potent agonist of the ORL1/KOR-3 receptor (Ki = 55 nM); displays no affinity for opioid receptors, including μ, δ, κ1 and κ3 receptors (Ki >1000 nM). Displays a...
T75897 Orphanin FQ(1-11) TFA
Orphanin FQ(1-11) TFA, a fragment of orphanin FQ or nociceptin (OFQ/N), acts as a powerful NOP receptor (ORL-1; OP4) agonist, exhibiting a K i of 55 nM. It lacks affinity for μ, δ, κ1, and κ3 receptors (K i >1000 nM), de...
T38100 Betamethasone 21-phosphate (sodium salt hydrate)
Betamethasone 21-phosphate is a synthetic glucocorticoid.1It prevents increases in macrophage and eosinophil numbers in bronchoalveolar lavage fluid (BALF) and decreases in blood leukocyte numbers in a guinea pig model o...
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